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Since 1963, the Guide for the Care and Use of Laboratory Animals has served as a primary, contemporary guide for animal care and use in the United States. No. eBook files are now available for a large number of reports on the NAP.edu website. It might be an acceptable sole means of evaluation in situations such as farm animal or other outdoor settings but not in more conventional laboratory animal settings. Committees are used so that different ideas and approaches can be presented, discussed, and resolved. . You can pre-order a copy of the book and we will send it to you when it becomes available. The new version of the Guide with about 200 pages suggests the minimum standards and offers numerous recommendations in this field. Minimum animal performance criteria for space are provided. This was deleted and the ’96 Guide just refers to controlling temperatures within plus or minus 2?F of the recommendations stated in Chapter 2. In the ’96 Guide there is added narrative stating that aseptic surgery should accommodate the species and complexity of the surgery. Veterinary care. The ’96 Guide has been partially reorganized and rewritten. The title of Chapter 1 has been changed to ‘Institutional Policies and Responsibilities.” Institutions, institutional objectives, and institutional personnel vary widely. The final version of this book has not been published yet. In the section Surveillance, Diagnosis, Treatment, and Control of Disease, the statement regarding daily observation of animals is amplified to reflect that more frequent observations may be needed in such instances as postoperative recovery, illness, or physical deficits. Effective sanitation can be achieved with the appropriate combination of temperature and time of exposure of the surfaces, with actual temperature varying from 143-180?F or more as a function of time. Group housing is encouraged. The item Some uses of laboratory animals represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Biddle Law Library - University of Pennsylvania Law School. . The Guide acknowledges that new information may influence how and why things are done the way they are; IACUCs must be responsibly flexible as our base of knowledge grows. This process has been very effective and has served the scientific community and animals used in research well. 8th ed. Each committee has been charged with the task of formulating appropriate guidelines, taking into consideration such critical factors as species of animals, research uses of animals, settings in which animals are used, necessary resources, and ethical considerations. There is more emphasis on individual case-by-case evaluation of the hazards and the risks posed rather than such broad categorizations. The importance of rodent health surveillance programs is emphasized. Anderson Cancer Center, Columbia University, College of Physicians & Surgeons, Professor Emeritus, University of Southern California, Southwest Foundation for Biomedical Research, © Institute for Laboratory Animal Research, Behavioral Management is a Key Component of Ethical Research, Moving Beyond the Absence of Pain and Distress: Focusing on Positive Animal Welfare, Micro- and Macroenvironmental Conditions and Stability of Terrestrial Models, The Role of Feed in Aquatic Laboratory Animal Nutrition and the Potential Impact on Animal Models and Study Reproducibility, About the Institute for Laboratory Animal Research, Chapter 1: Institutional Policies and Responsibilities, Chapter 2: Animal Environment, Housing, and Management, Committee to Revise the Guide for the Care and use of Laboratory Animals, Receive exclusive offers and updates from Oxford Academic, Copyright © 2021 Institute for Laboratory Animal Research. The Ag Guide evolved as an alternative to the Guide and ‘is intended to serve agricultural academic institutions and research organizations as a primary reference on the care and use of the major agricultural animal species in the United States in research and teaching that, for reasons of scientific rigor and applicability of results, must be conducted in simulated or actual agricultural production settings. William J. The chapter contents have been reorganized or expanded into sections on physical environment, behavioral management, husbandry, and population management. Accordingly, the revised Guide emphasizes the institution's responsibility to prepare IACUC members by providing ‘suitable orientation, background materials, access to appropriate resources, and, if necessary, specific training...” Another institutional responsibility is the conduct of an occupational health and safety program. Reports typically include findings, conclusions, and recommendations based on information gathered by the committee and the committee’s deliberations. Use of laboratory animals in scientific research and education. It was recognized that barns, corrals, pastures, and islands may be acceptable in many situations. Animals used in either biomedical or agricultural research may be housed in cages or stalls or in paddocks or pastures. This section has been expanded to include suggested criteria to use in evaluating the means for euthanasia. It is estimated that 50 to 100 million vertebrate animals worldwide — from zebrafish to non-human primates — are used annually. In general, topics related to husbandry are essentially unchanged. However, the AWRs based on the 1985 AWA are similar to the ’85 Guide recommendations. However, the general philosophy has changed. Special considerations such as physical restraint and multiple major surgical procedures are expanded. This has led to the development of 2 sets of guidelines, the Guide for the Care and Use of Laboratory Animals (Guide) and the Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (1988) (Ag Guide) . The NAS uses a ‘peer” process allowing the scientific community considerable input into animal care and use and self-governance via the Guide . Introduction. Cage space recommendations are no longer presented as absolute or ‘minimum.” The recommendations allow use of professional judgment and performance-based outcomes. Awrs were based on information gathered by the IACUC prepared to evaluate performance and outcomes of to... The information offered in the past decade, the Guide, objective data! Evaluation of the Guide emphasizes the institutional responsibility to ensure that IACUC members are well prepared to issues! For pitch of floors was discontinued in lieu of a recommendation that be. 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